Topical Pain Treatments

We are undertaking a number of studies to investigate the relative efficacy of topical non-steroidal anti-inflammatory drugs and capsaicin in osteoarthritis and neuropathic pain and to identify predictors of response.

These studies include:

• Conventional meta-analyses of placebo-controlled RCTs comparing treatment and placebo and overall treatment effects.
• Bayesian network meta-analysis comparing treatments via placebo.
• Individual Patient Data (IPD) meta-analysis to examine predictors of response.
• A pilot n-of-1 trial series to examine treatment effects, patient preferences, and predictors of response.